Playing on a wildcard (invitation) and was relegated to 117th world ranking, Istomin, 30, however, showcase the game ‘brave’ when defeated six-time champion, Djokovic 7-6 (10/8), 5-7, 2-6, 7-6 (7/5), 6-4 in a fierce battle that lasted 4 hours, 48 ​​minutes on Rod Laver Arena.

This is the first time that Djokovic was eliminated early in the tournament Grand Slam since Wimbledon in 2008, where he was eliminated in the second round by Russian player Marat Safin.